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Title:
TOPICAL REVIEW: Polymer gel dosimetry
Authors:
Baldock, C.; De Deene, Y.; Doran, S.; Ibbott, G.; Jirasek, A.; Lepage, M.; McAuley, K. B.; Oldham, M.; Schreiner, L. J.
Affiliation:
AA(Institute of Medical Physics, School of Physics, University of Sydney, Australia ; The authors of the article are listed in alphabetical order. The principle authors are Y De Deene and C Baldock, who contributed equally to the article ), AB(Radiotherapy and Nuclear Medicine, Ghent University Hospital, Belgium ; The authors of the article are listed in alphabetical order. The principle authors are Y De Deene and C Baldock, who contributed equally to the article ), AC(CRUK Clinical Magnetic Resonance Research Group, Institute of Cancer Research, Surrey, UK), AD(Radiation Physics, UT M D Anderson Cancer Center, Houston, TX, USA), AE(Department of Physics and Astronomy, University of Victoria, Victoria, BC, Canada), AF(Centre d'imagerie moléculaire de Sherbrooke, Département de médecine nucléaire et de radiobiologie, Université de Sherbrooke, Sherbrooke, QC, Canada), AG(Department of Chemical Engineering, Queen's University, Kingston, ON, Canada), AH(Department of Radiation Oncology, Duke University Medical Center, Durham, NC, USA), AI(Cancer Centre of South Eastern Ontario, Kingston, ON, Canada)
Publication:
Physics in Medicine and Biology, Volume 55, Issue 5, pp. R1-R63 (2010).
Publication Date:
03/2010
Origin:
IOP
DOI:
10.1088/0031-9155/55/5/R01
Bibliographic Code:
2010PMB....55R...1B

Abstract

Polymer gel dosimeters are fabricated from radiation sensitive chemicals which, upon irradiation, polymerize as a function of the absorbed radiation dose. These gel dosimeters, with the capacity to uniquely record the radiation dose distribution in three-dimensions (3D), have specific advantages when compared to one-dimensional dosimeters, such as ion chambers, and two-dimensional dosimeters, such as film. These advantages are particularly significant in dosimetry situations where steep dose gradients exist such as in intensity-modulated radiation therapy (IMRT) and stereotactic radiosurgery. Polymer gel dosimeters also have specific advantages for brachytherapy dosimetry. Potential dosimetry applications include those for low-energy x-rays, high-linear energy transfer (LET) and proton therapy, radionuclide and boron capture neutron therapy dosimetries. These 3D dosimeters are radiologically soft-tissue equivalent with properties that may be modified depending on the application. The 3D radiation dose distribution in polymer gel dosimeters may be imaged using magnetic resonance imaging (MRI), optical-computerized tomography (optical-CT), x-ray CT or ultrasound. The fundamental science underpinning polymer gel dosimetry is reviewed along with the various evaluation techniques. Clinical dosimetry applications of polymer gel dosimetry are also presented.
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