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Title:
What we can do and what we cannot do with fMRI
Authors:
Logothetis, Nikos K.
Affiliation:
AA(Max Planck Institute for Biological Cybernetics, 72076 Tuebingen, Germany, and Imaging Science and Biomedical Engineering, University of Manchester, Manchester M13 9PL, UK)
Publication:
Nature, Volume 453, Issue 7197, pp. 869-878 (2008). (Nature Homepage)
Publication Date:
06/2008
Origin:
NATURE
Abstract Copyright:
(c) 2008: Nature
DOI:
10.1038/nature06976
Bibliographic Code:
2008Natur.453..869L

Abstract

Functional magnetic resonance imaging (fMRI) is currently the mainstay of neuroimaging in cognitive neuroscience. Advances in scanner technology, image acquisition protocols, experimental design, and analysis methods promise to push forward fMRI from mere cartography to the true study of brain organization. However, fundamental questions concerning the interpretation of fMRI data abound, as the conclusions drawn often ignore the actual limitations of the methodology. Here I give an overview of the current state of fMRI, and draw on neuroimaging and physiological data to present the current understanding of the haemodynamic signals and the constraints they impose on neuroimaging data interpretation.
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Database: Astronomy
Physics
arXiv e-prints