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Title:
The cancer biomarker problem
Authors:
Sawyers, Charles L.
Affiliation:
AA(Howard Hughes Medical Institute, Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, New York 10065, USA.)
Publication:
Nature, Volume 452, Issue 7187, pp. 548-552 (2008). (Nature Homepage)
Publication Date:
04/2008
Origin:
NATURE
Abstract Copyright:
(c) 2008: Nature
DOI:
10.1038/nature06913
Bibliographic Code:
2008Natur.452..548S

Abstract

Genomic technologies offer the promise of a comprehensive understanding of cancer. These technologies are being used to characterize tumours at the molecular level, and several clinical successes have shown that such information can guide the design of drugs targeted to a relevant molecule. One of the main barriers to further progress is identifying the biological indicators, or biomarkers, of cancer that predict who will benefit from a particular targeted therapy.
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