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Title:
QRS slopes for assessment of myocardial damage in chronic chagasic patients
Authors:
Pueyo, E.; Laciar, E.; Anzuola, E.; Laguna, P.; Jané, R.
Affiliation:
AA(Instituto de Investigación en Ingeniería de Aragón (13A), and CIBER-BBN, Universidad de Zaragoza, Spain ), AB(Gabinete de Tecnología Médica, Universidad Nacional de San Juan, Argentina ), AC(Instituto de Investigación en Ingeniería de Aragón (13A), and CIBER-BBN, Universidad de Zaragoza, Spain ), AD(Instituto de Investigación en Ingeniería de Aragón (13A), and CIBER-BBN, Universidad de Zaragoza, Spain ), AE(Department ESAII, CREB, Universitat Politècnica de Catalunya, Barcelona, Spain)
Publication:
Journal of Physics: Conference Series, Volume 90, Issue 1, pp. 012077 (2007).
Publication Date:
11/2007
Origin:
IOP
DOI:
10.1088/1742-6596/90/1/012077
Bibliographic Code:
2007JPhCS..90a2077P

Abstract

In this study the slopes of the QRS complex are evaluated for determination of the degree of myocardial damage in chronic chagasic patients. Previous studies have demonstrated the ability of the slope indices to reflect alterations in the conduction velocity of the cardiac impulse. Results obtained in the present study show that chronic chagasic patients have significantly flatter QRS slopes as compared to healthy subjects. Not only that but the extent of slope lessening turns out to be proportional to the degree of myocardial damage caused by the disease. Additionally, when incorporating the slope indices into a classification analysis together with other indices indicative of the presence of ventricular late potentials obtained from high resolution electrocardiography, results show that the percentages of correct classification increase up to 62.5%, which means eight points above the percentages obtained prior to incorporation of the slope indices. It can be concluded that QRS slopes have great potential for assessing the degree of severity associated with Chagas' disease.
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